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Ondansetron
Clinical data
Trade namesZofran, Ondisolv, others
AHFS/Drugs.comMonograph
MedlinePlusa601209
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationby mouth, rectal, IV, IM
ATC codeA04AA01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Bioavailability~60%
Protein binding70%-76%
MetabolismLiver (CYP3A4, CYP1A2, CYP2D6)
Elimination half-life5.7 hours
ExcretionKidney

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Ondansetron is ... For chronic nausea in CKD zofran risks to fetus, however, many people find a dose of 1mg is fine, but needed at least twice daily, and if that doesn't work, is not enough, speak to your vet about increasing the frequency initially, Possible side effects include constipation, low blood pressure and sleepiness.

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